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Sunday, August 09, 2009

Do you know of any drug that was taken away from the market?

There is Vioxx and Celebrex, I know, I know but I don't know about any other.
I just came across with the site CenterWatch "recognized by many of the top media outlets and publications around the world as a leading source of information on the clinical trials industry."
I was searching for the 4th phase of clinical trials and this site was at the first page. That's how they explain the 4th phase:
"Phase IV studies, often called Post Marketing Surveillance Trials, are conducted after a drug or device has been approved for consumer sale. Pharmaceutical companies have several objectives at this stage: (1) to compare a drug with other drugs already in the market; (2) to monitor a drug's long-term effectiveness and impact on a patient's quality of life; and (3) to determine the cost-effectiveness of a drug therapy relative to other traditional and new therapies. Phase IV studies can result in a drug or device being taken off the market or restrictions of use could be placed on the product depending on the findings in the study."
Taken from the market? If anybody knows of a drug that was taken from the market because FDA studied it and came to the conclusion that it's not a good drug please let me know.

According to this same site:
"If a drug is approved, pharmaceutical companies may continue to conduct studies that compare the new drug—in terms of its safety, effectiveness, and cost—to other drugs already on the market or assess a drug's long-term effectiveness and its impact on the quality of a person's life."
If anybody knows about any site where I can find FDA real surveillance I would also like to know.

What about "evergreening"? I wrote about it last September here.

"‘Evergreening’ is the term used to describe the process by which the innovator patents trivial modifications of already-existing drugs which, in turn, extends their monopolies beyond the 20-year period granted for the original patent. It is a common practice in the pharmaceutical industry."

FDA and other countries regulatory agencies seems to be much more concerned in keeping the same drugs at the market. I will never understand how a drug that has killed during clinical trial, Cymbalta, is at the market.
Tracy Johnson hanging herself at Eli-Lilly's facilities during Cymbalta clinical trials was not enough or perhaps just an anecdotal evidence and not a scientific data.

Update:
*It's still at the market! There is a good article at USA Today about how the Vioxx case:
"Sen. Chuck Grassley, R-Iowa, says the FDA was worse than passive. Investigators for the Senate Finance Committee, which Grassley chairs, met Thursday with FDA researcher David Graham, lead scientist on a study presented in August at a medical meeting in France."

"Graham told the finance committee investigators that the FDA was trying to block publication of his findings, Grassley said in a statement. "Dr. Graham described an environment where he was 'ostracized,' 'subjected to veiled threats' and 'intimidation,' " Grassley said. Graham gave Grassley copies of e-mail that appear to support his claims that his superiors suggested watering down his conclusions."

Sunday, August 02, 2009

Senator Lyle Hillyard and the Loch Ness photography enigma


Many people is visiting this blog searching for this post I wrote about Senator Lyle Hillyard vacations.
The picture that was at the Senate site and the copy I had at this blog has disappeared but you can find this little image at Google's search. I have a copy of the photo but I will not publish it.
I'm writing this post to explain what has happened to those who come in search for the photography.

People are confused if it was a joke, the picture might be a photoshop, or if it's a real photography. I believe that explaining what it's really is about is better than deleting the picture and people are still discussing it at the Senate site where the photo was published without the picture now. The discussion is here.
I will take the opportunity to ask Senator Lyle Hillyard to pay attention at the severe harm psych medications are doing with US citizens and how terrible are US mental health hospitals.
There are lots of informations at Philip Dawdy's site Furious Seasons in case those who work for the Senator have a time to pay attention to this issue.
Senator Charles Grassley is already trying to make some change in the corrupt scheme medicine has became.
At this page of his site there is a good example:
July 9, 2009
Grassley, Kohl work to bring transparency to biomedical research funding

"WASHINGTON – Today Senators Chuck Grassley and Herb Kohl sent a letter to the National Institutes of Health (NIH), urging the federal agency to take steps to increase transparency of federally funded biomedical research. NIH is seeking public comment as it considers changes to its disclosure policy, and the senators made specific recommendations related to both individual researchers and academic institutions who receive NIH grants."

"The senators suggested that researchers be required to report their outside income to the nearest $1000, and that universities be required to complete a plan to manage the researcher’s potential conflicts of interest. Finally, they maintained that both the disclosures and the plan be available to the public via the NIH website."

"For the past two years, Grassley and Kohl have collaborated to push for increased transparency in financial relationships between physicians and the drug, device and biologic industries. As part of that effort, they have championed the Physician Payments Sunshine Act (S. 301) to require these industries to publicly report payments and gifts to doctors. Recently, identical provisions to those in S.301 were included in the health care reform discussion documents released by the Senate Finance Committee. Similar provisions were included in the House draft bill as well.
Grassley is Ranking Member of the Senate Committee on Finance. Kohl is Chairman of the Senate Special Committee on Aging. Below is the text of their letter to NIH."
Read the whole article here.

Tuesday, July 28, 2009

Stephany's views about the woman who killed her baby while taking antipsychotics

I copied this part of Stephany's post "The drugging of mothers: woman kills infant, allegedly taking psych meds for psychosis" because she describes how psychiatry is being practised today and this is from a woman who has witnessed and experienced the severe harm psych medications are doing.
I'm not anti-psychiatrist but with the amount of data available silencing is not an ethical attitude if one is concerned with the well-being of patients.

My thoughts

"This is a sad and gruesome story, and one that adds fuel to the discussion that has 2 sides. I've witnessed violence and aggression in people loaded up on psychiatric medications and I've seen them become calm and non-aggressive off of medications. Over the last decade, it has been my experience, not because I wanted it---to observe several psych wards and hundreds of people with the dx of Schizophrenia and psychosis. I have no vested interest in a pharmaceutical company and I am not what some people think: a anti-med scientologist. I'm just a mom who witnessed more than the average person, actually more than admittedly by inpatient psychiatrists---most told me they had not been inside state institutions or clinics --just their immediate revolving door psych wards, where indeed the door revolves because these meds cause symptoms as much as they want to believe they don't, people must understand what I witnessed is withdrawal psychosis when people go off of antipsychotics.

I am extremely concerned over the possibility of women and children being medicated by reason of a blanket screening for depression which could end up in wrong diagnosis and medication treatment that can cause extreme situations. It's what happened to my daughter at age 11, and Zoloft sent her running down roads and attempting to jump from cars on the freeway. Psychiatrists confirmed and agreed it was the Zoloft (anti depressant)back in 2001 that caused her extreme agitation and suicidal thinking/and resulting risky behaviors."
_____
"What medication was she taking? antidepressants? antipsychotics? were her medications changed too quickly? increased? decreased? all of these are factors that cannot be ignored. Of course this article is hearsay, but gives food for thought until all facts come out."

How can physicians remain silent? Can anybody explain it to me?

Monday, July 27, 2009

Hulu within the United States

Whenever I see it I feel part of the "rest of the world".

Wednesday, July 22, 2009

GlaxoSmithKline denies accusations of profiteering from the swine flu drug Relenza

I was watching BBC today and heard it:

"Price balance

Chief executive Andrew Witty denied accusations that the firm was profiteering from the demand for the swine flu drug.

He told the BBC that the firm had invested up to $2.5bn (£1.5bn) in the past three years to ensure that it could meet the government's demand for the drug.

And Mr Witty added that the firm was not charging more than it did for other seasonal flu drugs.

It was reported that the firm was charging the NHS £6 for each dose of Relenza, which cost it £1, but the company said this was "wrong".

Mr Witty would not be drawn on the costs of manufacturing the drug, but said typically the production cost was about 25% of the sale price.

"We are trying to strike a balance between society and our shareholders, who want to see a return on the risks we take.""(emphasis mine)

I heard that! The phrase I have emphasized is at BBC's site.
Is it me or this phrase sounds a little bit hypocrite?

Valproate Sodium, Depakote, lowers baby's IQ

Liverpool, UK - 22 July 2009:

"Interim results of a study being conducted by scientists at the University of Liverpool suggest that children aged three years and younger, who are born to women taking the anti-epileptic drug sodium valproate whilst pregnant, are likely to have an IQ of six to nine points lower than average.

The research, in collaboration with Emory University in the US and the Central Manchester University Hospitals NHS Foundation Trust, tested more than 300 three-year-olds in the UK and US, whose mothers took one of four anti-epilepsy drugs (AEDs) whilst pregnant. The preliminary findings suggest that children exposed to the drug sodium valproate had lower IQ results than children exposed to other AEDs, regardless of the mother’s IQ. The results also took dosage, duration of pregnancy and mother’s consumption of folic acid whilst pregnant, into account."


"Professor of Clinical Neuropsychology at the University, Gus Baker, said “Our research looked at how exposure to sodium valproate and other AEDs in the womb affected children’s everyday life – in particular their IQ, memory and language abilities from one to six years of age.”"

Whole article here.

Thursday, July 16, 2009

Corporate crime in the pharmaceutical industry by John Braithwaite

Click to enlarge and see some of the laboratories listed.

Excerpt from the preface:

"This book is an industry case study of corporate crime. It attempts to describe the wide variety of types of corporate crime which occur within one industry. When I tought a course on corporate crime at the University of California, Irvine, in 1979 I found that students had an amorphous understanding of the subject as an incomprehensible evil perpetrated by the powerful. Part of the purpose of this book is to fill this gap by describing many examples of corporate crime, examples which show the depth and seriousness of the crime problem in the pharmaceutical industry."

The book, published in 1983, is costing U$ 613,00 at Amazon and was not reprinted.
Do you have any idea why?
Anyway... There is a .pdf version that can be downloaded here.

Tuesday, July 07, 2009

The vast majority of people don't have a clue about what we are talking about

Whenever I try to talk about the death of people because of psych-drugs the same old happens: people don't know and I look like a lunatic.
I always tell to those who have to know because they work as psychologist or something related to go to Philip Dawdy's Furious Seasons because his blog is the best when we are talking about the horrors, yes horrors, that psych-drugs are causing.
Still people don't have a clue and don't want to know about it: it's too boring talking about it. I don't know but I was watching "The Constant Gardener" and there is this speech:

"
Arthur "Ham" Hammond: "So who has got away with murder? Not, of course, the British government. They merely covered up, as one does, the offensive corpses. Though not literally. That was done by person or persons unknown. So who has committed murder? Not, of course, the highly respectable firm of KDH Pharmaceutical, which has enjoyed record profits this quarter, and has now licensed ZimbaMed of Harare, to continue testing Dypraxa in Africa. No, there are no murders in Africa. Only regrettable deaths. And from those deaths we derive the benefits of civilization, benefits we can afford so easily... because those lives were bought so cheaply.""

Wednesday, July 01, 2009

Michael Jackson's cocktail to death


I've just found it at Susan's blog.
Her post is very good.
Of course it's not enough evidence and, as I heard yesterday while I was discussing about psych-drugs,:

"The benefits overweight the risks."
"If one person has committed suicide it does not mean that all of those who take antidepressants will do the same."
"I know many people whose lives was saved by an antidepressant."
"If not antidepressants what do you think is the cure for depression?"
"If the FDA leaves the drug at the market it's not harmful."
"There is not enough evidence proving these drugs are not safe."

I believe I will never stop hearing these arguments and they are strong for those who don't have a clue about what is really at stake when these drugs are prescribed.
Mr. Obama, where is the change? You are drugging your children and destroying lives and, please, don't tell us you don't know. You have received money from pharmaceutical industry during your campaign. Gradual change? Do you want more people to... blah blah blah...
Useless...

Kayoko Kifuji got a license to kill again

Rebeca Rilley parents are waiting for trial. Read it all at Furious Seasons.
I'm sorry for not writing. Last month I wrote too little and I'm not planning to be back this month.
I get too sad and angry. I'm not visiting my blog friends either. I have to be out for while because it's hard not to see any change.
I never forget any of my blog friends and you are all part of my life since you are the only who can understand what makes me so sad and angry about the use of psych-drugs and, of course, because you are all amazing people.
Love you all.

Bill Maher anti-pharma


"Vioxx reliefs the pain by killing you."

"Have you noticed that every prescription drug has a X or a Z in the name?... Are Americans really that dumb?... "I'm not a doctor but I can see that this is serious medicine!""

"I think they come up with a pill before they come up with a disease."

See the video and know about "Flacidix"

Bill Maher: using Duke University study contradicts himself



"A new Duke University study that shows that exercise is just as effective a cure for depression as Paxil and Zoloft."

I'm sorry Bill but you are claiming that Paxil and Zoloft are effective for depression but they are not.

Monday, June 29, 2009

Bid4aCure raises 1.7 million Linden dollars at Second Life to help American Diabetes Association

Visit their site:

Lindens raised as of

8:00 pm SLT, 6/28/09

Welcome to Bid4aCure.org and thank you

for taking the time to visit our website.

Bid4aCure is an effort by a group of concerned residents of the popular online virtual world of Second Life to raise both awareness and contributions for the real-world organizations: The American Diabetes Association and Diabetes UK. This June we held our third Bid4aCure benefit drive and it was our most successful one yet, having raised over 1.7 million Linden dollars! Our deepest appreciation goes out to all of our Sponsors and those who donated so generously to this effort.

If you want to know more about the benefit events that took place during the month of June 2009, click the Events link above. To learn more about Bid4aCure, our past fundraising drives, and view letters we have received from the American Diabetes Assoc. and Diabetes UK, click on the About link. Although our 2009 Bid4aCure drive has ended in Second Life, you may still donate to these organizations directly by clicking on their logos at the top right of this page.



L$1,769,155

Thursday, June 25, 2009

Farrah Fawcet and Michael Jackson - R.I.P.

I'm speechless... Susan did posts about both deaths. Just heard about Michael Jackson and had heard about Farrah Fawcet in the afternoon.

R.I.P.

Update:

Brian Oxman is saying at CNN that Michael Jackson was taking too much prescription drugs and that he has advised the family.
He is a close friend of Michael.

Update 2:
Philip Dawdy, Furious Seasons's journalist, has written a post about Michael Jackson cocktail of drugs:
"That he died of what appears to be sudden cardiac death makes me wonder greatly about what his toxicology results will be."
And this article about CNN and Fox criticizing long-term use of antidepressants:

"That said, I want to make it clear that I am not blaming Zoloft and Paxil for Jackson's death. I am not saying that taking either drug will give any specific person a heart attack. But I am saying that, for now, that the two anti-depressants are inextricably entwined and linked to the death of MJ."
Read the whole article.

Drugging children with psych-drugs: Peter Breggin views (repost)

This is from Independent on October, 2006 when Peter Breggin was in Ireland and I've copied it all because he raises many issues related with drugging children that are still not unfold.
I didn't know that Cymbalta, the antidepressant that Traci Johnson was taking in the clinical trial, was being tested for "stress urinary incontinence" and she was not informed that it was also being tested as an antidepressant.


'The greatest child abuse of our time is the mass drugging of our children'

By Gareth O'Callaghan
Sunday October 15 2006

TRACI Johnson wanted with all her heart to go back to college. She was a tall 19-year-old brunette with stunning good looks, and a spirited, determined young woman.

She was healthy, with no history of physical or emotional difficulties, such as depression. Those closest to her described her as upbeat, an active volunteer and someone who loved life.

She had enrolled as a voluntary participant in a trial to test a new drug for "stress urinary incontinence" for which she was paid US$750 a day - the money she intended to put towards her college fees.

She commenced taking the drug in January 2004. Four weeks later, Traci Johnson hanged herself using a scarf in the shower room.

By local state laws, she was not old enough to legally drink a beer; she could not even rent a car. Yet she was deemed mature enough to decide to take an experimental drug on a daily basis.

The drug she was testing is now a widely prescribed antidepressant.

I am talking to the world-renowned psychiatrist Peter Breggin, who is visiting Ireland this week.

"The real child abusers are my colleagues in psychiatry who have led the way," were his exact words. Then he slowly repeats it.

"They are child abusers. The greatest child abuse of our time is the mass drugging of our children."

Having reflected on the words he chooses to describe doctors who prescribe harmful psychiatric drugs to young children and teenagers in order to "cure" depression or Attention-deficit Hyperactivity Disorder(ADHD), I find he makes sense.

His time in court over many years has honed his ability for instant dramatic effect. He has acted as a witness in defence of individuals who took cases against the giant drug companies they claimed ruined their lives and almost stole their sanity and their will to live.

Many of them were awarded large fortunes in what became highly publicised landmark cases in the States. But, more important than money, they got back their dignity and their identity.

"I've had dozens of cases of anti-depressant-induced violence, suicide, psychosis, mania. In one extreme case, a man knocked down a policeman with his car in order to grab the policeman's gun to shoot himself; in another case, a man drove his car into a barrier in an attempt to kill his wife, whom he thought had an alien lurking inside her; in both cases these were clearly caused by the drugs.

"People become victims of the 'Spellbinding Effect', as I call it, leaving them at the mercy of these drugs because they don't realise they're being harmed; and they can even get a false impression that they're doing better than ever before, when in fact they 'The FDA gave a legal rationale for its silence: "Some clinical trial data are considered 'trade secrets', or commercially protected information, and thus are exempted from release under the Freedom of Information Act"'

have an unrealistic euphoria."

Breggin walks his own talk. It would be difficult to contradict the statements that are flying like a professional boxer's jabs and hooks, because everything he says is based on almost 50 years of well-practised research. But is depression not all about common sense?

"The problem is that the common sense approach, which is also the most profound approach to depression, leaves biological psychiatry high and dry, because [psychiatry] treats people as if they're broken mechanical devices that can be tinkered with by a person who knows much less about the brain than the average mechanic knows about your car.

"They take the most complex subtle human problems - how to find meaningful work, how to find love, how to live in a world full of violence and disappointments, how to overcome childhood experiences of abuse and oppression - all of these subtle difficult problems that are human problems can be resolved through a whole range of human alternatives from counselling to philosophy and religion, and they treat them in the most ignorant way as mechanical issues."

Pharmaceutical companies and many of his erstwhile colleagues have not disguised their contempt for him since the day he stepped out from the elite ranks of his closely guarded profession.

He says that new pharmaceuticals are branded as wonder drugs with certain beneficial properties. When rivals catch up and start making the same claims for their brands, the PR changes and even greater claims are made.

"So it's all games with words, played to influence the public," Breggin claims.

Breggin, who turned 70 recently, has spent much of his professional life criticising what his own profession stands for, namely the trigger-happy tendency on the part of many doctors and psychiatrists to prescribe harmful, addictive drugs for depression - a condition that is far more receptive to a loving, expressive, empathic relationship.

"We know now, and it's shown in scientific research that these drugs do cause addiction, and they predispose youngsters when they get into their 20s to use cocaine because their brains have become conditioned by [named brand drugs] which are in the same class of stimulant as cocaine.

"These drugs, for the first few weeks, usually have a flattening effect on the child's behaviour. They replace spontaneous behaviour with compulsive behaviour. It is the suppression of normal brain function."

HE IS the author of 20 bestselling books; one of them, Toxic Psychiatry (1991), made for tough reading. It was the first time we were told head-on about the dangers of some anti-depressants possibly leading to suicide. It took until 2004 for some manufacturers to accept this and include such a warning on the drug's accompanying instructions leaflet.

He says that some drug companies have "led the way in suppressing critics and research. They control the drug market - they've led the way in that regard. I'm not sure what the answer's going to be, because the battle is so lopsided, but then David did bring down Goliath".

So what's all this scientific stuff about chemical imbalances in the brain? I ask.

"There is no evidence whatsoever that depression is caused by a biochemical imbalance. There is none!" He says it is an idea promoted by certain drug companies.

"The only biochemical imbalances that we know of in the brains of people labelled 'mental patients' are the ones caused by psychiatric drugs and electric shock."

Some anti-depressants, he says, have been dubbed "the magic pills". In the States it was hip and trendy to be "popping" these pills and attending "a shrink".

One in five Irish adults takes Selective Serotonin Reuptake Inhibitor (SSRI) anti-depressants (CSO statistics, 2006). That's over half a million people. Are you surprised by such a high figure? I ask.

He sighs. "I was hoping that the Irish had more sense than the Americans - but in this regard it sounds a lot like America. It's a great misfortune, because there's actually very little valid scientific evidence for the effectiveness of these drugs. The way they have gotten approval in the United States is by ignoring all the ways they are no better than a sugar pill, while focusing on the small number of very limited studies that show they are only little better than a sugar pill!

"On the other hand, they cause a lot of harm. They call this the Risk Benefit Ratio. The risk of taking these drugs is rather large; all kinds of physical and psychiatric problems result from taking the drugs, while the benefit is usually small "

Drug companies in the US have paid out millions insettlements.

Breggin was one of the medical experts who evaluated cases on behalf of the claimants, including cases in which individuals died of acute diabetic coma or pancreatitis while being treated with a drug. There have also been lawsuits from people who claimed they suffered severe mental and behavioral abnormalities, including mania, suicidal tendencies, violence, and the onset of a condition called Tardive Dyskinesia (permanent drug-induced abnormal physical behaviour, as a result of taking certain prescribed drugs, characterised by involuntary jerky movements of the face, tongue, jaws, trunk, and limbs).

The drug industry says there is a legitimate concern that the fear surrounding their drugs could mean some patients are not prescribed them. They say it is important that necessary anti-depressant treatments are available to all patients who need them, including children and adolescents, and they say: "Information about the safe use of these products is made publicly available."

Is it really? I don't think so. Seven months prior to the international launch of the drug she was testing, the news of Traci Johnson's suicide started to leak out into small local newspapers around the States. Eventually, it made national headlines. Four others, each diagnosed with depression, also died by suicide while participating in the same trials.

According to an investigation by the London Independent newspaper, all five deaths were "hidden" by the American Food and Drug Administration (FDA). The FDA gave a legal rationale for its silence: "Some clinical trial data are considered 'trade secrets', or commercially protected information, and thus are exempted from release under the Freedom of Information Act."

The FDA has directed the manufacturers of all anti-depressant medications to add a "black box warning" that describes the increased risk of suicidal ideas and fixations in children and adolescents given anti-depressant medications.

Traci Johnson wasn't suffering from depression. She was part of a clinical test into a drug for stress urinary incontinence. Unknown to her, this drug was also being tested as an anti-depressant. I doubt she might have partaken in such tests if she'd known that nine months later the tablets she'd swallowed would carry a "black box" suicide warning.

Peter Breggin, MD, will speak at a day-long conference entitled 'Healing Depression without Drugs or Electric Shocks', next Saturday, October 21, at the Burlington Hotel, Dublin. Contact Ticketmaster.ie for details

- Gareth O'Callaghan

Wednesday, June 17, 2009

SSRIs Do Cause Permanent Sexual Dysfunction - Video testimony



This is the testimony of a man who had the courage to speak about PSSD.

Saturday, June 13, 2009

Romantic love is over, welcome solitude

No, this title is not mine. It's from a Brazilian thinker and I've read it so many time ago that I forgot who is the author and I did not read the entire article just took a glimpse but I still have this phrase in my mind.
I cannot come to a conclusion and I'm still thinking about it because I'm not even sure if romantic love has ever existed since I cannot point an era where the vast majority of people were happily married or in love for a lifetime.
I've been hearing people of all ages telling about their love experiences. Most people are alone, men and women and some are discussing about love but I can see many ideas repeating themselves.
Sex is easy but it's not a prerogative of any fight or a characteristic of our times.
It has always been like even at Victorian age.
I thought I had something definitive to say but it's still in my mind: Romantic love is over, welcome solitude.
I believe there's a way out of this. Humans are not supposed to be alone although one has to know to be alone to be with someone else.

Friday, June 12, 2009

SSRI group testimony about PSSD - Post-SSRI Sexual Dysfunction and sperm damage caused by Paxil

I have already written about SSRI-Sex group however it seems that it's a hard issue to raise for many reasons and obviously because sexuality is not a very easy issue to talk.
I decided to publish one e-mail with the story of a member to make it easier to understand the problems people are facing.
PSSD has an article at Wikipedia and is reported to physicians. However it seems to be something out of the planet to some doctors. Now it's being unfold that Paxil damages sperm as you can read here at Philip Dawdy's Furious Seasons.

"Hi all,
I've been a member for 3/4 weeks now and I would like to share my experience with PSSD:
I'm 32, male. Used Zoloft for Nov.2008 till end of Feb..2009 (close to 4 months). Started with low dose (probably 20 mg and increased it to 40 briefly when I started having tinnitus. So, reduced it to 20, didn't help with the tinnitus. So, tapered off of it after taking 10mg for about a week.) So, all this lasted for about 4 months. And needless to say, soon after started taking it, sexual dysfunction started (trouble getting aroused, lack of morning erections, etc). I didn't notice this in the initial days as I was masturbating by watching porn and didn't have much difficulty getting or maintaining an erection. But towards the end of this 4 month period, I noticed some trouble getting an erection. But what followed after the withdrawal from SSRI was worse.
About 2/3 weeks after completely stopped taking zoloft, I started having erectile dysfunction. My PCP did the bloodwork, treadmill test etc for heart functioning etc and found nothing wrong. He offered to give Viagra, which I declined, because only I knew that he was treating the wrong symptom. My ED was not because of circulation problems or anything like that. My symptoms included trouble getting aroused, lack of interest in sex/masturbation, lack of sensation down there, no pleasure in orgasm, ED, soft erections, delayed orgasm, no interest in talking to the opposite sex, etc. Basically I was like living while dead.
I tried using L-arginine for the ED, but had to stop it because of severe heartburn, which was a side effect of it. So, wouldn't know if that would have helped. And just when I was about to give up and prepare for the long haul, one day it happened. I got slightly aroused one day while thinking about the opposite sex. 2 days after this, I woke up with an erection. And this recovery is into the 2nd week now and while I still have soft erections, I do seem to get an erection when I want it. The libido seems to be coming back slowly. And ability to have feeling like pleasure, sadness and anger seem to be coming back as well. After going thru this for a little more than 2 months, I'm in 2nd week of recovery. I'm not yet at a pre-SSRI level sexually, but I'll take what I can get.
Ya only thing I did differently 1 or 2 days before the recovery was do some yoga. I can't say if it helped because it was just 1 day. But it doesn't hurt to do some yoga & exercise & eating right."
This is one of many testimonies.

UPDATE:
There is not a single member of this group that has an authentic profile not even it's owner.
This is a pale idea of what is really going on.
There are many messages and some of them only a person from another planet would read it without crying.
People from the group want their problems to be heard that is one of the reasons I have published two posts about the group that strangely enough is not known by those who should be highly interested in the problem: psychiatrists.
There's only one (1) video at YouTube of a man who had the guts to tell his story.
I'm sure I'm helping others to know about the problem and if Vornan, the group's owner, thought that I'm causing any harm to any person he would have come here.
I follow this group since it's creation in 2005.

Thursday, June 11, 2009

Blog anniversary - I dedicate this day to...

...the main reason why I started this blog: GREED and BAD SCIENCE.
For all of those who are profiting at the expenses of other people health, suffering, and lives
, those who see money as an end in itself no matter what the consequences.
Amazingly enough they are few compared to the huge amount of people who are severely harmed by the medicaments they sell.

I want to thank all my blog friends who have helped me thought this year and Traci Johnson, the photo of my avatar, whose smile has helped me keep going.
I know somewhere up there she is happy.

Wednesday, June 10, 2009

SSRIs detox clinics? (repost)

The British Bruce Lee, who has been using all his skills and weapons to bring the truth on Paxil/Seroxat, just shot a post on detox clinics for SSRi's withdrawal.
But we were told that SSRIs are not addictive over and over again. Why on earth there are private clinics in UK to help people tapering these drugs?
There are plenty data here and all over the Web claiming that not only these drugs are highly addictive but that they are the hell to withdraw. Bob Fiddaman found out this insightful paragraph:

Treating addiction to antidepressants is therefore among the most difficult of all addictions to treat, precisely because its true nature is so poorly understood and because doctors may inadvertently work against the best clinical interests of their patients. Faced with the prospect of a suicide, doctors often reach for a prescription pad so that they can be seen to be "doing" something. However, when a successful suicide has used antidepressants the doctor is not blamed but thought to have done his or her best to "help" the patient. Nothing could be further from the truth. Prescribing a mood-altering drug makes it less likely that the patient will find a solution to internal as well as external problems because the sense of equanimity is artificially induced. -
Dr Robert Lefever

Monday, June 08, 2009

SSRIs withdrawal hell and lasting side effects after quiting the drug - two testimonies

As many people are not aware that SSRIs and SNRIs are powerful drugs that have serious side effects and withdrawal is a hell I'm reposting this. One of the stories is about long lasting withdrawal symptoms after being off Effexor.


"I've saved these two stories on July 21,2005 from the site
drugawareness.org . Unfortunately the site has changed and the database of 276 stories are no longer online. Two of them are here. Get the Kleenex.


This is Survivor Story number 24.
Total number of stories in current database is 276


12/15/2003
The Effexor Nightmare
The drug company should have let us known that this could happen to us.

Six years ago I had became very depressed. Little did I know that depression ran in our family, starting with my grandmother, my mother and then myself.

I tried for three long agonizing years to beat the beast in my life. Finally, I decided to go and talk to my doctor about my depression and she put me on Paxil. I don't even remember half of what I did for about a month. All I could do was cry and sleep. She then decided to put me on Effexor, which has been just as bad. I have gained so much weight that I find myself still depressed.

In all I have gained 53 pounds. I also have other side effects that I had no idea the Effexor was causing until I starting researching the drug. I have muscle tremors that my doctor put me on seizure medicine for. I also have headaches, and I cannot sleep. An example is that I am writing this and it is almost three in the morning and I get up at five to get my children ready for school. This is another problem. I do not feel like doing anything because I feel numb almost all the time and if I forget to take my medicine I become very aggressive and outspoken in a very ugly manner and this is not the person I am nor do I want to continue to be this way.

I don't feel like cooking, cleaning, washing, or doing everyday activities and I also have problems with my memory and that is a bad thing when you have children to do things for everyday, and it takes a toll not only on me but my family. I am only 33 and I want to be able to live a normal life and that will never be until I get this medicine out of my system. I want to be a good wife and mother, and not have my family suffer with me through this hell. If I had known what this crap would do to me I would have never swallowed that first pill. I will continue to pray for all those that are taking the drug Effexor and I hope that you will do the same for me.

Maybe, just maybe we can beat this addiction to a drug that was suppose to help us overcome depression. And the drug company should have let us known that this could happen to us. What if it was their wife, their child, or their relative that had to live the Effexor nightmare? Would it make a difference to them then or would it be just another dollar in their pockets?
Gary Kelley
flycaster@earthlink.net




This is Survivor Story number 199.
Total number of stories in current database is 276

7/1/2000
Unprepared for the Horrendous Withdrawal from Effexor (with an update 4 months later)

"Sometimes it felt as if my brain was shuddering in my skull…"

I realize that this is what most would consider a long letter. However, it is only a brief summation of my own personal experience. Please, especially those of you who are parents or grandparents, teachers or counselors, just take the two minutes it takes to read it, then just put it in the back of your mind. Or pass it on.

Anti-depressants are quite often being cavalierly dispensed to the population in general. Also, they are prescribed to help kids who've been on Ritalin for years get through the difficult process of the cessation of that drug. And now the manufacturers of these drugs are planning to produce it in smaller doses for their next target population: pre and elementary school aged children! These drugs have a very high percentage rate of undesirable and sometimes dangerous side effects.

Several years ago I broke my wrist, which caused me to develop a rare condition known as Reflex Sympathetic Dystrophy. One of the medications I was given to try to control the pain was Effexor. Effexor is a serotonin reuptake inhibitor, or an SSRI. These drugs are commonly known as anti-depressants. Prozac is probably the most commonly known drug in this class. I was on this drug for less than 6 months when, for reasons of my own, I decided I wanted to get off. That's when my nightmare began.

One cannot just stop taking these drugs. There is a tapering off process which must be followed. This is because there are very often serious and debilitating withdrawal symptoms. However, I was not told of these symptoms, and I now know that the doctor did not know about them, either. He told me only that nightmares were a common occurrence during this process, and that I might also experience "mild, flu-like" symptoms and "slight confusion." During this initial, original prescribed tapering off process, which was supposed to take about 2 weeks, I experienced vivid and terrifying nightmares. I could not shake these off for hours after I had wakened. Since I was extremely tired, I napped a lot. Each time I napped, there would be a nightmare, and the process would repeat itself several times daily. I really was unprepared for their intensity and lasting after-images.

Then came the day I was to stop taking it. To make a long story short, these were some of my symptoms: A weird visual thing would happen for about a second, about 4 times a minute. I can only compare it to what it feels like to try to track the arrow of the mouse across the page. But I knew it was not my eyes that were doing this, I could feel it was my brain. (October, 2000: I've just found out that the term for this is "staccato vision"). I also experienced what people who have this call a sensation "like electric shocks" or "jolts" to my whole body which also occurred for a split second every 15 seconds or so. When these occurred at night, in the dark, they were accompanied by a flash of white light. It's as if I were "whiting out" (instead of "blacking out") for just a split second every 15 seconds or so. These incidents began to increase in intensity and began to be accompanied by panic and/or paranoia flashes. Eventually, just moving caused such dizziness and disorientation that I had to hold onto whatever was around me to walk. Sometimes it felt as if there were a magnet to one side of me, pulling me that way. The "slight confusion" I experienced is something I can only imagine is what beginning Alzheimer's patients must feel like during the initial stages of their eventually terminal mental decline during the time when they are still aware that something is really going wrong. Sometimes it felt as if my brain was shuddering in my skull a sensation that has come to be called "Brain Shivers" or "Brain Flips" by many. Numerous other things were happening as well, but I don't want to get too long-winded here. I just want to give you all some idea of some of the kinds of things that were happening.

So, I made an appointment with the prescribing doctor, and a friend was kind enough to take me there. But the doctor did not believe me! He said that it couldn't be the Effexor, that I probably had some neurological problems and that if the symptoms persisted, I should see a neurologist. But I KNEW it was the Effexor, so I went home, took another pill, and felt fine within the hour. Then I got on the 'net. What I found there was astounding! Tons of people, all with the same things happening to them, reaching out to anonymous others and saying, "Help! What is happening to me?" These I found on bulletin boards, NOT on product information sites put up by the people who are selling the stuff.

I tried calling the Drug Company to find out what was happening to me and how to stop it. I never did reach them. Fortunately for me, my primary care physician had heard of these symptoms and knew how to deal with them. She advised a long, slow tapering off process, telling me that it could take one to two months for me to be able to get off. Also fortunately for me, she told me to take as long as I needed.

It took me 10 MONTHS! During that time, the symptoms mentioned above continued, although diminished enough for me to be able to function almost normally. But other things began to happen. I saw things out of the corners of my eyes, which were not there. We all do that, but this was pretty constant. One thing I saw which I never told anyone about until it had stopped was a big, hairy rat about 1 foot long, scurrying around corners. Keep in mind that I was not on this drug because I was in any way mentally unbalanced, it was merely to help with the pain. I saw, and still see occasionally, a pinpoint of violet shimmering light. Also, things would seem to be moving out of the corners of my eyes. A spot on the wall, for example, I would think was a spider crawling until I looked directly at it, when I would realize it was just a spot on the wall. These things did not scare me, but they were frequent and startling and bothersome.

I took my last little crumbs of Effexor in September of 1999. End of story?

Unfortunately, no. It is now the end of July, 2000, and I still experience some of the same symptoms, although they are manageable. I also have experienced monstrous headaches. The first one, back in September, lasted 4 days. I thought I was going to die. I even told my son that I might die. I debated about that for a while, but did not want him to wake up and find me dead one morning. Fortunately, I'm still here. My headaches began to decrease in length, and now they seem to last only 2 hours or so. They go away within one minute. Sometimes I'm just achy all over. I guess that experience is the "mild, flu-like" symptoms I'd been warned about. I still have days I call "my stupid days", and they usually signal the beginning of episodes lasting several days, involving vertigo, dizziness, short anxiety attacks, some euphoria occasionally, the "brain shivers", and numerous other weird symptoms, and culminating in a headache. Then I'm fine for however long it lasts. Sometimes I feel whole body tremors, not enough to make me twitch, and they are not unpleasant, but they're there and they shouldn't be.

I am concerned about this. I want to know why, after not taking this drug for so long, I am experiencing this "discontinuation syndrome", and when will it stop? I have not yet found the answer.

I finally did get in touch with the Drug Company to ask them these questions and they took down all my information. They have never explained why, and they have never followed up. They would not talk to me about my symptoms, they would only talk with my doctor. And this was not OK because the doctor did not believe me! (This was not the prescribing doctor who hadn't believed me when I first tried to get off, this was the doctor who'd prescribed the tapering off process.) But I told her to call them and talk to them, and it was pretty easy for them to shine her on, since she didn't believe me anyway. And they sent her a letter advising a slow tapering off of the drug, which I'd already done, of course, AND a "report" from a closed symposium on SSRIs sponsored by the a drug company 'way back in 1996! (Which, of course, did not address the issue.)

The more research I've done on these things, the angrier I become. Because the drug companies have known about these things for years. Many people and their families have gone through much, much worse than I have. Some people have never been able to get off the drugs.

Now, what would YOU do if you were manufacturing these things? You'd probably say' "Whoa! We need to stop selling these things until we can find out what's causing this. We'd better get in touch with each and every one of those people who are having these extreme reactions, do whatever we can to help them, and to identify what it IS about them that makes them react differently than those who have no problems with the medication." Well, not only are these companies not doing this, they are manufacturing the drugs in smaller doses so that CHILDREN can take them! Yes, Prozac is currently being tested on pre-school aged children! And although these drugs have not YET been approved for use in children, the numbers of children aged 6-12 being prescribed Prozac has risen from 41,000 in 1995 to 203,000 in 1996. Currently, in 2000, 2.3 million children in the U.S. are on anti-depressants. The official literature on these drugs says that they are safe for pregnant women to take! And there are documented cases of newborns being born with the more evident withdrawal symptoms (which the drug companies are ignoring because nobody can prove it. Isn't that horrible?!). The companies that manufacture these things are re-naming Prozac "Seraphim" or something and doctors are prescribing it for PMS!

Are these drugs harmful to absolutely anyone who takes them? Of course not. And for many, these drugs have proven to be beneficial. However, they are NOT only being prescribed for major, long-term depressions, but for such things as the Holiday Blues and teenage angst! But the percentage risk for horrible and even deadly side effects is extremely high. (See the 3rd link below.)

Please, unless you are chronically depressed or have something really, really severe, stay away from this class of drugs. And please, NEVER EVER put a child on these things! I am an intelligent, articulate, resourceful middle-aged woman. When a wave of panic starts to wash over me, or any other of these weird things start to happen, I can tell myself to just hold on, it's just the after-effects of the drug, it will go away, I should take a deep breath and relax, etc. Do you think a child or a newborn could do the same? I can't imagine what it would be like to be a child in school and to suffer the kind of confusion I've been through and manage to learn anything, let alone be involved in a physical activity or sport! This has been going on for nearly 2 years with me, and I don't know when it will end!

Thank you for taking the time to read my story. This has been a BRIEF synopsis of what my life has been like for the past two years. And it's nothing compared to what others have been through.

Update, October, 2000:

In the few months since I wrote this, I found that these continued withdrawal effects after not haven taken the drug for a long time is a phenomena which has not one but two names: PANES (Persistent Adverse Neurological Effects) and "Intractable Withdrawal". This phenomenon was noted as early as 1996, before I began taking Effexor. How can the pharmaceutical companies deny the existence of something that has occurred enough to even have a name?

Several months ago I was driving with my son on the freeway at night and I felt fine. Out of the blue, a wave of disorientation and that peculiar form of dizziness I associate with my "Effexor Episodes" came upon me. I found myself in the middle of two lanes with no remembrance of which one I had come from. I was too scared to look in the rear view mirror to see what was behind me. I heard my son yell, "What are you doing?" A car was breaking to the left of me. I asked my son which lane I should go into and he told me to go right. Fortunately the freeway was not crowded. I was dizzy and scared and felt as if I was going to pass out. Soon there was an exit and I took that off the freeway and my son continued the drive home. I have not driven at night since.

I am a 50 year old woman with an excellent driving record. I made it. I feel sure that if there had been more cars on the freeway there would've been a terrible accident. Children from the ages of 6 up are being prescribed these drugs. They are getting their learners permits and at age 16 are given driver's licenses after passing very easy tests. Maybe you or a loved one will be in a car next to one someday. Maybe you'll be in an airplane piloted by a pilot who's missed a dose, directed by an air traffic controller who's trying to get off this stuff. Maybe you'll be next to a taxicab driver or a bus driver or a commuter who is suddenly euphoric or has a momentary panic attack. I won't drive at night, and am careful about where and when I drive in the daytime. But I really don't think that many can afford to do that. I think they'll just drive and hope for the best. And that is really, really scary to me.
Louise Mangan